Stress Regulation

5.0 (1 reviews)

Stress Regulation is a non-sedating, multi-pathway, stress and mood formula designed to calm nervous system reactivity while supporting relaxed focus, a healthy cortisol response, emotional balance, and greater resilience to everyday stress.* It addresses both the immediate response to stress and the longer-term processes involved in adaptation and resilience.*

Key Benefits

Supports calmness and relaxation without sedation*1-9

Helps maintain a healthy cortisol response during stress*1-9

Supports emotional resilience and a balanced mood*1-9

Combines clinically studied Sensoril® Ashwagandha with targeted amino acids, botanicals, and cofactors*1-2

Supports GABAergic signaling and nervous system balance*5

Supports the body’s ability to adapt to everyday stressors*1-9

Provides active vitamin B6 and magnesium to support neurotransmitter synthesis and healthy nervous system function*6,7

Helps establish nervous system readiness for recovery and practitioner-guided protocols*

Stress Regulation features BioActive Carbon® Technology which facilitates toxin removal and cellular energy, ensuring systemic resilience and long-term health.*8,9

One-Time Purchase
$35.95

Supplement Facts

Ingredient Amount % DV
Vitamin B6 (as pyridoxal 5-phosphate) 3 mg 176%
Magnesium (as magnesium glycinate complex) 30 mg 7%
L-Theanine 150 mg †
Sensoril® Ashwagandha Extract (Withania somnifera) (root, leaf) 150 mg †
GABA (Gamma-aminobutyric acid) 125 mg †
Taurine 100 mg †
Magnolia Extract (Magnolia officinalis) (bark) 60 mg †
Lemon Balm Extract (Melissa officinalis L) (leaf) 50 mg †
Saffron Extract (Crocus sativus L) (stigma) 30 mg †
Phosphatidylserine (from sunflower seeds) 25 mg †
BioActive Carbon® Technology Fulvic Blend — Humic Shale (containing Fulvic & Humic Acid) 10 mg †

† Daily Value (DV) not established.

Ingredients

Sensoril® Ashwagandha with GABA, L-Theanine, Saffron, Taurine, Magnolia & More 

Rather than focusing on cortisol alone, it combines a clinically studied dose of Sensoril® Ashwagandha with GABA, L-Theanine, saffron, taurine, magnolia, and targeted cofactors to support healthy cortisol response, calming neurotransmitter pathways, mood balance, and nervous system regulation.*1-9  

This layered approach provides support for stressful moments while helping build resilience over time, creating a stronger foundation for recovery, detoxification, and whole body wellness.* 

Together, these ingredients support the full stress-response cycle to promote a calmer, more balanced, and adaptable response to everyday stress.* 

How to Use

Adults take 2 capsules daily, with or without food, or as directed by your healthcare professional. For best results, use consistently as part of your daily wellness routine.

Clinical References

Auddy, B., et al. “A Standardized Withania somnifera Extract Significantly Reduces Stress-Related Parameters in Chronically Stressed Humans: A Double-Blind, Randomized, Placebo-Controlled Study.” Journal of the American Nutraceutical Association, vol. 11, no. 1, 2008, pp. 50–56.

Pandit, Srikanta, et al. “Effects of Withania somnifera Extract in Chronically Stressed Adults: A Randomized Controlled Trial.” Nutrients, vol. 16, no. 9, 2024, article 1293. PubMed Central, https://doi.org/10.3390/nu16091293.

National Institutes of Health, Office of Dietary Supplements. Ashwagandha: Is it helpful for stress, anxiety, or sleep? Fact Sheet for Health Professionals.

Sarris J, McIntyre E, Camfield DA. Plant-based medicines for anxiety disorders, part 2. CNS Drugs. 2013;27(4):301-319.

Yoto A, et al. Amino Acids. 2012;43(3):1331-1337. PMID: 22203366.

Jackson PA, et al. Effects of Saffron Extract Supplementation on Mood, Well-Being, and Response to a Psychosocial Stressor in Healthy Adults. Front Nutr. 2021;7:606124.

Sensoril® is protected under U.S. Patent 6,713,092 and is a registered trademark of Natreon, Inc.

Data on File. Microbe Formulas LLC. 2026.

Hriciková S, et al. Humic Substances as a Versatile Intermediary. Life. 2023;13(4):858.

National Institutes of Health, Office of Dietary Supplements. Vitamin B6 Fact Sheet for Health Professionals.

National Institutes of Health, Office of Dietary Supplements. Magnesium Fact Sheet for Health Professionals.

Product Label (PDF) Download

Frequently Asked Questions

How does Stress Regulation differ from other stress support supplements?

Many stress supplements center on a single ingredient or cortisol alone. Stress Regulation uses a clinically studied dose of Sensoril® Ashwagandha within a broader formula that also supports GABAergic signaling, relaxed focus, mood balance, emotional resilience, and nervous system regulation.* This multi-pathway design supports both day-to-day calm and longer-term stress adaptation without sedation.*

Can Stress Regulation be taken with other products?

Elevated stress is a common factor in people’s lives. Over time elevated stress can lead to systemic inflammation, interfere with detoxification and proper gut function, affect proper immune function, metabolism, and increase the rate of neurodegeneration. Reducing the effects of stress can help optimize healing and detoxification. Stress Regulation integrates well into any protocol or recovery plan or can be used as a stand-alone if needed to support daily resilience.

Should Stress Regulation be taken with food?

Stress Regulation may be taken with or without food. Taking it with food may improve tolerability for individuals who are sensitive to supplements.